The LT5 requires silicates... Prestone Extended Life info states:
Prestone® Extended Life 5/150 Antifreeze/Coolant is phosphate,
silicate, and borate free. This coolant uses a special chemistry and technology (basically HOAT/OAT) that extends the life of the corrosion inhibitor package so that it lasts for five years or 150,000 miles (whichever comes first), and is safe for all cars and light trucks.
Prestone® Extended Life 5/150 Antifreeze/Coolant has been approved by General Motors under their DEX-COOL® specifications and is compatible with other DEX-COOL® approved coolants.
Also, OAT (Organic Acid Technology) & HOAT (Hybrid Organic Acid Technology) based antifreezes should not be used with the LT5 engine so you need to take a peak at this chart>>
http://www.eetcorp.com/antifreeze/Coolants_matrix.pdf
As a 'rule of thumb'>>>
Even though raw coolant has no color, manufacturers dye the coolant to help discern different types of coolant. Most cars manufactured before 1995 were designed to run the traditional "green stuff," which contain silicates that coat and protect cooling system components. However, these silicates deplete more quickly, requiring coolant changes every two years or 24,000 miles. Bascially, post 1995 GM cars use Dex Cool and can not use silicated (aka Green Stuff) coolant and vice versa pre 1995 can not and should not use Dex Cool (or non silicated/OAT/HOAT) coolants.
I am not a coolant engineer or chemist, but base my comments on research and talking to those who understand coolant chemistry and automotive applications. I DO agree that this subject is difficult due to manufacturers vague information on formulation and attempts the 'one size fits all aka "safe for all cars and light trucks" which is blantly not true. Called marketing driving "facts" for market share.